Cover image

Crystal structure of SARS-CoV-2 stem–loop 5 (SL5) (PDB id: 9E9Q; Jones CP, Ferré-D'Amaré AR. 2025. Crystallographic and cryoEM analyses reveal SARS-CoV-2 SL5 is a mobile T-shaped four-way junction with deep pockets. RNA 31: 949–960). The T-shaped four-way junction of the coronavirus SL5 structural element provides a starting point for examining the structures of larger RNA motifs and their interactions with other molecules. Image highlighting the four arms of the junction. The RNA backbone is depicted by a gray ribbon. The bases within the arms of the junction are colored respectively in blue, red, yellow, and cyan. Cover image provided by X3DNA-DSSR, an NIGMS National Resource for Structural Bioinformatics of Nucleic Acids (R24GM153869; skmatics.x3dna.org). Image generated using DSSR and PyMOL (Lu XJ. 2020. Nucleic Acids Res 48: e74).