Thermodynamic control of mismatch discrimination for extensive splicing regulation of PKM pre-mRNA

TABLE 1.

The oligonucleotides applied in thermodynamic studies

Name Sequence
sSSO CGGAGUCA
sSSO1 CLGGAGUCA
sSSO2 CGGALGUCA
sSSO3 CGGAGUCLA
sSSO4 CGGAGUCAL
sSSO5 CUGGAGUCA
sSSO6 CGGAUGUCA
sSSO7 CGGAGUCUA
sSSO8 CGGAGUCAU
  • The bolded and underlined font indicates the positions of mismatches within the sSSO/sI9 duplex. UNAs and LNAs are marked with uppercase U and L, respectively.

This Article

  1. RNA 31: 475-485