Thermodynamic control of mismatch discrimination for extensive splicing regulation of PKM pre-mRNA

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FIGURE 2.
FIGURE 2.

The sequence of duplexes formed by SSO with exon 10 (A) or intron 9 (B) fragments. Duplexes formed by sSSO applied in thermodynamic studies constitute shortened models of SSO interactions with exon 10 (C) and intron 9 (D). The red font indicates mismatch positions in SSO/I9 and sSSO/sI9 duplexes.

This Article

  1. Published in Advance December 30, 2024, doi: 10.1261/rna.080212.124 RNA 31: 475-485

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