Cytoplasmic regulation of the poly(A) tail length as a potential therapeutic target

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FIGURE 1
FIGURE 1

. Schematic representation of a CPEB bound to the CPE in the 3′ UTR of the target mRNA. The structure of the two RRMs and the ZZ-box is adapted with permission from Afroz et al. (2014). The intrinsically disordered N-terminal half of CPEBs is indicated, along with the 5′ and 3′ UTRs of the mRNA, the open reading frame (ORF), and the poly(A) tail.

This Article

  1. Published in Advance January 13, 2025, doi: 10.1261/rna.080333.124 RNA 31: 402-415

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