Rational design yields RNA-binding zinc finger domains with altered sequence specificity

TABLE 3.

Double mutant design of ZnF

Double mutant no. N22 N32
1 R R
2 R H
3 D R
4 D H
5 E R
6 E D
7 E E
8 E Q
9 E H
10 E S
11 Q R
12 Q H
13 H R
14 H H
15 S R
16 S D
17 S E
18 S Q
19 S H
20 S S

This Article

  1. Published in Advance December 10, 2024, doi: 10.1261/rna.080329.124 RNA 31: 150-163

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