FIGURE 1.
Structural consequences of the s2m_omicron mutation. (A) Secondary structure of s2m_Wuhan and s2m_omicron. The position of the deletion is marked with a red line. Artificial nucleotides for T7 in vitro transcription are shown as lowercase letters. (B) NMR solution structure of the three main states of s2m_omicron. One representative of each substructure is shown with the loop nucleotides highlighted in color. (C) Sequence alignment of s2m_Wuhan and s2m_omicron with the deletion appearing as gap. The nucleotide numbering corresponds to the genomic position of the original Wuhan version -29000.
