A conserved triple arginine motif in OMA-1 is required for RNA-binding activity and embryo viability

TABLE 1.

Nematode strains used in this work

Strain Genotype
WRM66 oma-1(ne5035[oma-1::GFP]) IV; oma-2(ne5034[degron::oma-2), neSi101[sun-1p::tir-1::mRuby::eft-3 3'UTR; Cbr-unc-119] V
WRM92 oma-1(spr24[ne5035*(oma-1(RRR–AAA)::GFP)]) IV; oma-2(ne5034[degron::oma-2), neSi101[sun-1p::tir-1::mRuby::eft-3 3'UTR; Cbr-unc-119] V
COP2772 oma-1(knu1284[ne5035*(oma-1(P110-H182del)::GFP)]) IV; oma-2(ne5034[degron::oma-2), neSi101[sun-1p::tir-1::mRuby::eft-3 3'UTR; Cbr-unc-119] V

This Article

  1. Published in Advance August 27, 2025, doi: 10.1261/rna.080611.125 RNA 31: 1575-1588

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