The oligonucleotides containing N7-regioisomer of guanosine: influence on thermodynamic properties and structure of RNA duplexes

The aromatic-to-anomeric regions of the 2D ¹H-¹H NOESY spectra recorded for duplexes containing: (A) the 7G-A mismatch in the 5′G7GC/3′CAG context, (B) the 7G-A mismatch in the 5′C7GG/3′GAC context, (C) the 7G-G mismatch in 5′G7GC/3′CGG context, and (D) the 7G-G mismatch (in 5′C7GG/3′GGC context). Significant NOEs discussed in the text are marked in magenta. Sequential connectivity paths for the two strands are displayed in green and blue lines. For complete sequences and residue numbering, see Figure 1.