Discrete measurements of RNA polymerase and reverse transcriptase fidelity reveal evolutionary tuning

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FIGURE 7.
FIGURE 7.

Comparison of substitution rates on template DNA1. (A) Error rates for T7 and Induro on DNA1 and IRES-Cas subdivided by error type. Substitution error profiles of DNA1 and IRES-Cas for (A) T7 RNA polymerase and (B) Induro RT. (C) Fraction of substitution errors for Induro using the DNA1 (gray) or IRES-Cas (yellow) template.

This Article

  1. RNA 30: 1246-1258