Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis

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FIGURE 4.
FIGURE 4.

(A) Native gel electrophoresis with 9xTEL DNA incubated with twofold dilutions of TMPyP4 (highest concentration: 3200 nM) in NaCl/KCl (left half of gel) or LiCl (right half). (B) As in panel A but with 9xnoGG DNA. (C) Native gel of 9xTEL DNA incubated with twofold dilutions of PDS (highest concentration: 1600 nM) in NaCl/KCl (left half) or LiCl (right half). (D) As in panel C but with 9xnoGG DNA.

This Article

  1. Published in Advance June 25, 2024, doi: 10.1261/rna.080043.124 RNA 30: 1213-1226

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