Regulation of the Drosophila transcriptome by Pumilio and the CCR4–NOT deadenylase complex

TABLE 5.

Transcript group criteria for feature evaluation

Group Characteristics Definition
1 0 Perfect Transcripts that had no perfect PRE sites present in the 3′ UTR
2 1 + Perfect with effect Transcripts that had at least one perfect PRE site present and the differential expression showed a significant effect (LFC ≥ log2(1.3), q-value ≤ 0.05)
3 1 + Perfect with no effect Transcripts that had at least one perfect PRE site present but the differential expression showed no significant effect (LFC ≥ log2(1.3), q-value ≤ 0.05)
  • Defining criteria for the transcript groups 1, 2, and 3: Groups were defined based on whether or not the 3′ UTR of the transcript contained a PRE site that perfectly matched the consensus sequence 5′-UGUANAUA and whether or not the transcript appeared significantly repressed by Pum.

This Article

  1. RNA 30: 866-890