TABLE 4.

Functional and statistical relationship of Pum-regulated, bound, and PRE-containing genes

PRE location:		5′ UTR	CDS	3′ UTR
Pum-regulated and PRE-containing	P-value	0.778	0.171	<0.001
Pum-regulated and PRE-containing	log₂(FE)	−0.403	1.105	1.953
Pum-regulated and Pum-bound	P-value	<0.001	<0.001	<0.001
Pum-regulated and Pum-bound	log₂(FE)	1.943	1.977	1.956
PRE-containing and Pum-bound	P-value	<0.001	0.013	<0.001
PRE-containing and Pum-bound	log₂(FE)	1.220	0.605	1.249
Pum-regulated, PRE-containing, and Pum-bound	P-value			<0.001
Pum-regulated, PRE-containing, and Pum-bound	log₂(FE)			0.575

(UTR) Untranslated region, (CDS) coding sequence, (FE) fold enrichment. P-values from permutation test, n = 1000.

Regulation of the Drosophila transcriptome by Pumilio and the CCR4–NOT deadenylase complex