NMR characterization and ligand binding site of the stem–loop 2 motif from the Delta variant of SARS-CoV-2

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 6.
FIGURE 6.

Canonical coordinates based on ribose carbon shifts of s2m. (A) Each square corresponds to a can1*/can2* combination of 1 nt derived from its ribose 13C chemical shifts. Specific nucleotides are annotated. Red squares indicate C2′ endo and black squares indicate C3′ endo conformation. Loop and internal loop nucleotides are annotated. (B) Secondary structure of s2m Delta.

This Article

  1. Published in Advance April 2, 2024, doi: 10.1261/rna.079902.123 RNA 30: 779-794

Current Issue

  1. July 2026, 32 (7)
  1. Current Issue
  1. Alert me to new issues of RNA