2′-O-methylation (Nm) in RNA: progress, challenges, and future directions

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FIGURE 2.
FIGURE 2.

Nm writers. (A) Box C/D snoRNPs deposit Nm on rRNA, snRNA, at some sites in tRNA, and at internal sites in mRNA. (B) Stand-alone enzymes deposit Nm on tRNA, at the 5′ cap of mRNA, and in viral RNA. Stand-alone enzymes have also been proposed to deposit Nm at some internal mRNA sites. Created with BioRender.com.

This Article

  1. Published in Advance March 26, 2024, doi: 10.1261/rna.079970.124 RNA 30: 570-582

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