Structural and functional effects of inosine modification in mRNA

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FIGURE 1.
FIGURE 1.

(A) ADAR-catalyzed deamination of adenosine to inosine in RNA changes the H-bonding potential of the modified nucleobase. (B) Hydrogen bonding patterns for G–C, I–C, and A–U Watson–Crick base pairs. (C) Hydrogen bonding patterns for G–U, I–U, and I–A wobble base pairs. H-bonds are shown as dashed lines.

This Article

  1. Published in Advance March 26, 2024, doi: 10.1261/rna.079977.124 RNA 30: 512-520

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