FIGURE 6.
Disruption of the MOG-5 region predicted to interface with SACY-1 and the mimic of human (R525H) show overlapping proofreading phenotypes. Splicing assay of RNA from synchronized L3 populations. RT-PCR products were run on 6% polyacrylamide gels. The strains are indicated above each lane. The sequence of the alt. spliced 3′ss is shown to the right of each gel. Quantification and standard deviation from three independent experiments for each condition are shown below the gels.
