FIGURE 4.
Features of WT versus sacy-1(G533R) A3 events. (A) Histogram. X-axis: relative position of the splice site that increases usage with sacy-1(G533R) compared to the other site of the pair; negative number indicates 5′ direction. (B) Sequences of two splice site pairs randomly chosen from the 187 pairs where the distal site has a closer match to the consensus sequence than the proximal site. (C) Sequences of the only two events found where sacy-1 (G533R) increases usage of a distal splice site ≥27 nt away from the proximal site. (D) Sequences of the only two events found where three adjacent splice sites are used.
