Turn-on RNA Mango Beacons for trans-acting fluorogenic nucleic acid detection

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FIGURE 6.
FIGURE 6.

Mango Beacons display specificity to RNA single-stranded nucleic acid triggers. Mango Beacon MIIB + 4i fluorescence after the addition of an RNA, DNA, reverse sequence of the RNA (Reverse RNA), or a double-stranded RNA (dsRNA). (D) Addition of TO1-Biotin dye (100 nM final), (S) addition of Mango Beacon (50 nM final), (T) addition of Trigger (100 nM final). Sequences are shown in Table 5.

This Article

  1. Published in Advance January 24, 2024, doi: 10.1261/rna.079833.123 RNA 30: 392-403

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