TABLE 1.
5′ end of RNAs recognized by antiviral innate immune sensors
| RNA 5′ ends | RIG-I | IFIT1 | IFIT5 |
|---|---|---|---|
| 5′-P | − | − | ++ |
| 5′-PPP/PP | ++ | ++ | ++ |
| m7G (cap 0) | ++ | ++ | + |
| m7G N1 (cap 1) | − | + | − |
| m7G N2 (cap 2) | − | − | − |
-
(++) Interaction.
-
(+) Weak interaction.
-
(−) No interaction.
