AptaDB: a comprehensive database integrating aptamer–target interactions

TABLE 1.

Comparison of AptaDB main data with other aptamer databases

Database Number of interactions Aptamer structural information Aptamer-related information Target information Application information Experimental information
AptaDB (http://lmmd.ecust.edu.cn/aptadb/) 1350 Minimum free energy structure, centroid structure, dot-bracket notation Aptamer chemistry, length, GC content, molecular weight, molarity of 1 μg/μL, number of G-quadruplexes, G-score Cross-referenced from other databases: UniProt, PubChem and ATCC, protein secondary structure, small-molecule structure, visual representation of cells Functional classification and specific application Binding buffer, binding affinity, experimental figure, experimental description
Apta-Index (https://www.aptagen.com/apta-index/) 770 Only minimum free energy structure Aptamer chemistry, length, GC content, molecular weight, nmol/OD260, μg/OD260 Only target categories and names No Binding buffer, binding affinity
Aptabase (https://www.iitg.ac.in/proj/aptabase/) 605 No Length, GC content Only target categories and names No Binding buffer, binding affinity

This Article

  1. RNA 30: 189-199