FIGURE 2.
Properties of PCCRs in the IO category. The equilibrium free energy ΔG (A), the R-scape E-value (Rivas et al. 2017) (B), the frequency of A-to-I RNA editing sites (C), and the frequency of forked eCLIP peaks (D) near PCCRs supported inside and outside (IO category) in at least k cell lines. See Supplemental Figures S4 and S5 for the I and O categories, respectively. Statistically discernible differences at the 0.01% significance level and nonsignificant differences are denoted by (****) and “ns,” respectively (two-tailed Mann–Whitney test). Whiskers indicate 95% confidence intervals for proportions.
