Transcriptome-wide probing reveals RNA thermometers that regulate translation of glycerol permease genes in Bacillus subtilis

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FIGURE 8.
FIGURE 8.

Schematic representing possible model of regulation. At low temperatures, the 5′ UTR for both glpF and glpT showed little reactivity and are therefore depicted as folded and import is low (red). As temperature increases, the 5′ UTR reactivity increased and is depicted as melting from a structured RNA to a more unstructured RNA. This in turn increased expression and could result in increased import (green) of glycerol (G) and glycerol-3-phosphate (G3P) by GlpF and GlpT, respectively. These solutes could function as chemical chaperones to protect proteins during this temperature increase.

This Article

  1. RNA 29: 1365-1378