
Mapping in vivo reactivity onto a known RNA motif. The tyrS T box riboswitch from B. subtilis contains a k-turn in the lower portion of the structure (PDB ID: 2KZL). This particular k-turn is characterized by three bulged A residues followed by two GA base pairs. The bulged A residues show moderate (orange) to strong (dark orange) DMS reactivity at 37°C.










