FIGURE 2.
(A) The internal loop of helix h24 in 16S rRNA in contact with the anionic U677•G713 pair is shown in cyan. Please note the stacking of the two G776 and G775 and the usual wobble pair at G778•U804. (B) The anionic U677•G713 pair with the contact to the O2′ of A777 in the 16S rRNA of E. coli (from 8B0X, Fromm et al. 2023). For comparison, the distances in PDB 7K00 (Watson et al. 2020) corresponding to N1(G)…O4(U), N2(G)…N3(U) are 2.7 Å and 3.0 Å and those for N2(G)…O2′(A777), O2(U)…O2′(A777) are 3.1 Å and 2.4 Å. The red spheres represent water molecules in close proximity.
