Disruption of the Aspergillus fumigatus RNA interference machinery alters the conidial transcriptome

Deletion of RNAi components results in altered conidial transcriptome. (A) Genes that were identified as significantly differentially expressed in mRNA-seq. Differences were considered significant if q ≤ 0.05 and |log₂ (MRN)| ≤ 1 by all four tools. The number next to the bar indicates the total number of differentially expressed genes (DEGs). (B) GO-Slim analysis (using FungiDB.org) for Biological Process generated using differentially expressed genes from conidia as input gene sets. Up- and down-regulated differentially expressed genes (left panel) as well as the number of differentially expressed genes (right panel) are indicated.