Duf89 abets lncRNA control of fission yeast phosphate homeostasis via its antagonism of precocious lncRNA transcription termination

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FIGURE 5.
FIGURE 5.

Duf89 genetic interactions with fission yeast inositol pyrophosphatases. (A) S. pombe wild-type, single-mutant, and double-mutant strains with the indicated duf89, asp1, and siw14 alleles were spot tested for growth at the temperatures specified. aps1Δ was synthetically lethal with duf89Δ and siw14Δ. (B) The indicated fission yeast strains were assayed for Pho1 acid phosphatase activity. (C) Inositol pyrophosphatases convert 1,5-IP8 to either 5-IP7 or 1-IP7 as shown.

This Article

  1. Published in Advance March 7, 2023, doi: 10.1261/rna.079595.123 RNA 29: 808-825

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