Adaptive sampling for nanopore direct RNA-sequencing

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FIGURE 4.
FIGURE 4.

Effect of depletion and enrichment on Chromosome 11. (A) Loess curve for depletion of Chromosome 11. The log2 gene expression based on read counts from the NS run was plotted against the observed enrichment in sequenced bases in AS versus NS. The dashed red line (=1) indicates the threshold for deletion/ enrichment. (B) Loess curve for the enrichment of Chromosome 11 as in A. (C) Normalized coverage (autoscale group to [0–38]) of CKAP5 in NS and AS with enrichment or depletion of Chromosome 11, as indicated.

This Article

  1. RNA 29: 1939-1949