Fission yeast poly(A) polymerase active site mutation Y86D alleviates the rad24Δ asp1-H397A synthetic growth defect and up-regulates mRNAs targeted by MTREC and Mmi1

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FIGURE 8.
FIGURE 8.

MTREC and Mmi1 targets accumulate in pla1-Y86D cells. Venn diagrams depicting numbers of overlapping and nonoverlapping mRNAs or noncoding RNAs that were up-regulated in red1Δ cells (Lee et al. 2013) or mRNAs up-regulated at the nonpermissive temperature for mmi1-ts cells that are considered the “Mmi1 regulon” (Chen et al. 2011).

This Article

  1. Published in Advance August 16, 2023, doi: 10.1261/rna.079722.123 RNA 29: 1738-1753

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