Autorecoding A-to-I RNA editing sites in the Adar gene underwent compensatory gains and losses in major insect clades

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FIGURE 6.
FIGURE 6.

Adaptive proteomic diversification of Adar autorecoding site. (A) The adaptiveness of RNA editing is achieved by temporal–spatial flexibility of controlling the proteomic diversity, avoiding the pleiotropic effect of DNA mutations. (B) Correlation between the global Adar activity and the autorecoding level of S > G site in different samples of D. melanogaster. (C) The stabilizing effect of the Adar autorecoding site.

This Article

  1. Published in Advance July 14, 2023, doi: 10.1261/rna.079682.123 RNA 29: 1509-1519

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