A-MYB/TCFL5 regulatory architecture ensures the production of pachytene piRNAs in placental mammals

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FIGURE 5.
FIGURE 5.

A model for the A-MYB/TCFL5 regulatory architecture of mouse male meiotic cells. The model incorporates hypotheses from Li et al. (2013), Özata et al. (2020), Wu et al. (2020), Choi et al. (2021), and this study. The figure highlights the roles of A-MYB and TCFL5 in regulating pachytene piRNA genes and direct targets of pachytene piRNAs during mouse spermatogenesis.

This Article

  1. Published in Advance October 14, 2022, doi: 10.1261/rna.079472.122 RNA 29: 30-43

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