Biological solution conditions and flanking sequence modulate LLPS of RNA G-quadruplex structures

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FIGURE 7.
FIGURE 7.

CD spectra for 3′-flanking sequences in the absence and presence of spermine. (A) Absence and (B) presence of 0.3 mM spermine. 3′-mixed (yellow), 3′-A9 (green), 3′-C9 (blue), and 3′-U9 (purple). All spectra are buffer corrected and the 3′-A9 sequence is corrected for the spectrum of A9. Samples are in the background of 10 mM HEPES (pH 7.5) and K150N10M0.5.

This Article

  1. RNA 28: 1197-1209