CpG and UpA dinucleotide representation in the chicken transcriptome, ISGs and avian inteferon-α and -γ genes. A comparison of (A) CpG and (B) UpA dinucleotide representation in chicken ISGs and avian interferon genes (listed in Supplemental Data Tables S8, S10) with chicken mRNA transcriptome sequences (of coding sequence lengths ≥450 bases). Chicken ISGs were identified through homology searching for homologs of human ISGs listed in Supplemental Data Table S8, Schoggins et al. (2014), Burke et al. (2019), and Shaw et al. (2021). Differences in dinucleotide representations over defined G + C content ranges specific for each IFN gene class were analyzed using the independent samples t-test.
