Comparison of CpG- and UpA-mediated restriction of RNA virus replication in mammalian and avian cells and investigation of potential ZAP-mediated shaping of host transcriptome compositions

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FIGURE 10.
FIGURE 10.

Comparison of CpG and UpA composition in RNA viruses infecting mammals and birds. Observed/expected ratios of (A) CpG and (B) UpA RNA viruses (listed in Supplemental Data Tables S11, S12) infecting mammals and birds. Ratios have been overlaid on values for avian (chicken) mRNA sequences to provide context. Analysis restricted to coding sequences of length >450 bases.

This Article

  1. Published in Advance June 8, 2022, doi: 10.1261/rna.079102.122 RNA 28: 1089-1109

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