Organization of minicircle cassettes and guide RNA genes in Trypanosoma brucei

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FIGURE 10.
FIGURE 10.

(A) Oligo(U) tails are attached preferentially to sense strand transcripts whose last (3′-most) templated nucleotide is U (canonical and canonical gRNA genes). (B) The last nucleotide of expressed canonical and noncanonical gRNA genes is usually T, but the proportion of genes ending with a T nucleotide is significantly lower for noncanonical gRNA genes.

This Article

  1. Published in Advance April 12, 2022, doi: 10.1261/rna.079022.121 RNA 28: 972-992

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