(A) A rough phylogenetic tree of the coronavirus family. Some strain names are indicated along the branches. Sequences can be found in the alignments shown in Figures 1B and 2. Based in part on Smith et al. (2014). (B) Selected sets of aligned sequences of the first 80 nt of betacoronavirus genomes, except the Sarbecovirus, which are shown in Figure 2 (for a rough tree of coronaviruses, see Supplemental Figure S1). The color code is such that base paired segments are colored identically (purple, SL1A, red, SL1B, green, SL2, and yellow, SL3, with the TRS sequence in cyan). Sequences in bold were isolated from infected humans. The dates are those of database deposition.
