The universally conserved nucleotides of the small subunit ribosomal RNAs

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 26.
FIGURE 26.

A conserved base quadruple. Two conserved Watson–Crick pairs form a quadruple via the noncanonical type XI A55–G357 pair. Since C54 and A55 are consecutive in sequence, formation of the quadruple stabilizes a sharp turn in the RNA backbone. This quadruple forms the core of cluster 14, which contacts elongation factors EF-G and EF-Tu.

This Article

  1. Published in Advance February 3, 2022, doi: 10.1261/rna.079019.121 RNA 28: 623-644

Current Issue

  1. July 2026, 32 (7)
  1. Current Issue
  1. Alert me to new issues of RNA