VfoldMCPX: predicting multistrand RNA complexes

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FIGURE 4.
FIGURE 4.

Predicted melting curve (A) and secondary structures (B) for the 3WJ-forming two-strand system (Liu et al. 2011). (A) The heat capacity is computed from the total partition function of all the possible 2D structures and the total concentration of two strands (23.5 µM). The first peak at T = 59.5°C matches the experiment-determined melting temperature T = 57.6°C (Liu et al. 2011). (B) The base-pairing probability-inferred structures at T = 37°C, T = 55°C, T = 70°C, and T = 85°C, respectively. Two strands are shown in blue and red.

This Article

  1. RNA 28: 596-608