Nuclear magnetic resonance reveals a two hairpin equilibrium near the 3′-splice site of influenza A segment 7 mRNA that can be shifted by oligonucleotides

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FIGURE 5.
FIGURE 5.

Aromatic region near the diagonal of a 2D TOCSY spectrum of 2.0 mM HP2 showing direct exchange cross-peaks between two conformations, HP2-PK and HP2-HP. Temperature is 20°C and mixing time is 29 msec. Assignment of each chemical shift to HP2-PK or HP2-HP is available in Supplemental Table S2.

This Article

  1. Published in Advance January 4, 2022, doi: 10.1261/rna.078951.121 RNA 28: 508-522

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