Widespread genetic heterogeneity of human ribosomal RNA genes

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FIGURE 1.
FIGURE 1.

Multiple sequence alignment of human rRNA coding region in chromosome 21. (A) Schematic representation of four rDNA copies in human acrocentric chromosome 21 (GRCh38). rDNA copies are labeled by different colors. (B) Multisequence alignment of the coding regions of the chromosome 21 rDNA copies and KY962518 reference sequence. The differences are colored by red. rRNA coding regions are shown on the top. (C) Multisequence alignment of 28S rRNA. Asterisks indicate the position of small INDELs. (D) Multisequence alignment of two INDELs in 28S rRNA. Numbering on the left refers to 28S rRNA positions.

This Article

  1. RNA 28: 478-492