Cytoplasmic RNA sensors and their interplay with RNA-binding partners in innate antiviral response: theme and variations

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 2.
FIGURE 2.

RNA-binding protein partners of cytoplasmic RNA sensors. RLRs are in yellow. TRIM proteins are in blue. PACT, TRBP and other RNA binding proteins are in dark blue. Zinc-finger proteins are in pink. TBK1/IKKε are in green. IRF3 and NF-κB are in red. Stimulatory and inhibitory actions are highlighted by arrows and stop signs, respectively.

This Article

  1. RNA 28: 449-477