Cover image

E. coli RNA helicase HrpA in complex with RNAm (PDB id: 6ZWW; Grass LM, Wollenhaupt J, Barthel T, Parfentev I, Urlaub H, Loll B, Klauck E, Antelmann H, Wahl MC. 2021. Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility. Proc Natl Acad Sci 118: e2100370118). Escherichia coli HrpA is an ATP-dependent 3' to 5' RNA helicase with activity that appears to influence bacterial survival under antibiotic treatment. The RNA polyU model is displayed as a red ribbon with cyan block bases; protein is displayed as a gold ribbon. Cover image provided by the Nucleic Acid Database (ndbserver.rutgers.edu). Image generated using DSSR and PyMOL (Lu XJ. 2020. Nucleic Acids Res 48: e74).