Overview of glycolytic enzymes and their identification as RNA-binding proteins. According to the RBP2GO database, glycolytic enzymes are highlighted with a light gray box when one isoform of the enzyme was identified in global RIC approaches, a dark gray box when additionally RNA binding was validated and characterized beyond global approaches, and with white boxes when a protein is not listed as an RNA-binding protein in the RBP2GO database. Multiple amino acid alignments were conducted using the UniProt alignment tool. For every glycolytic enzyme, all isoforms were compared. Shown are always the lowest values for protein sequence similarity. For a detailed percentage identity matrix, see Supplemental Figure 1.
