Replication of alphaviruses requires a pseudoknot that involves the poly(A) tail

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FIGURE 6.
FIGURE 6.

Disruption and restoration of base triples in SINV pseudoknot. (A) GFP expression in BHK21J cells transfected with SINV replicons carrying the indicated changes in the pseudoknot. (B) Relative nanoluciferase expression of BHK21J cells transfected with SINV-Nanoluc replicons. Error bars indicate standard deviation of two experiments.

This Article

  1. Published in Advance July 29, 2022, doi: 10.1261/rna.079243.122 RNA 28: 1348-1358

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