Argonaute binding within human nuclear RNA and its impact on alternative splicing

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FIGURE 5.
FIGURE 5.

Validating the effect of AGO knockouts on alternative splicing. (A) Semiquantitative PCR validation of skipped exon events in AGO1/2/3 KO and AGO1/2 KO cells. (B) Quantitation of data shown in part A. Error bars represent standard deviation (SD). (*) P < 0.05; (**) P < 0.01; (***) P < 0.001 compared with WT by one-way ANOVA and Dunnett's multiple comparisons test.

This Article

  1. Published in Advance June 9, 2021, doi: 10.1261/rna.078707.121 RNA 27: 991-1003

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