Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation

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FIGURE 8.
FIGURE 8.

Summary of inhibition mechanisms of antibiotics impairing translocation. The inhibitory step for each antibiotic and the ability to halt (⊥) or slow down (ᛙ) the motions of ribosomal subunits during translocation is indicated. We consider a step as inhibited if it is >300-fold slower than in the absence of antibiotics.

This Article

  1. Published in Advance June 11, 2021, doi: 10.1261/rna.078758.121 RNA 27: 981-990

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