Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation

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FIGURE 6.
FIGURE 6.

Neo concentration-dependent effects. (A) Neo binding sites on the SSU (pink and violet) and LSU (dark green). SSU body and head are highlighted in blue and red, respectively, the LSU is gray. EF-G-dependent SSU body (light blue) and head swiveling (orange) were monitored in the presence of 0.2 µM (B) or 100 µM (C) Neo and compared to the uninhibited reactions (−AB).

This Article

  1. Published in Advance June 11, 2021, doi: 10.1261/rna.078758.121 RNA 27: 981-990

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