Ribosomal RNA degradation induced by the bacterial RNA polymerase inhibitor rifampicin

Colony forming units after treatment with rifampicin. Viable cells per mL of culture were measured by colony formation after serial dilution (10⁻⁶-fold) and plating on LB in the absence of antibiotic. Rifampicin was added at 0 min. The graph shows the average and standard deviation of colony forming units (cfu) from three biological replicates. Percentages represent normalization to the −2 min time point.