A noncanonical microRNA derived from the snaR-A noncoding RNA targets a metastasis inhibitor

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FIGURE 4.
FIGURE 4.

Identification of miR-snaR targets. (A) The intrahybrid base-pairing pattern between the miRNA and its target mRNAs are predicted by UNAFold using Ago-qCLASH hybrid reads for miR-snaR (left) and all other miRNAs (right). (B) Venn diagram showing seed-matched miR-snaR targets that appear in two or more hybrids from three Ago-CLASH data sets: HEK293, HCT116, and HCT116 Drosha-KO. Targets that appear in multiple data sets are shown. (C) Base-pairing pattern between miR-snaR and targets identified in B. Watson–Crick base pairs are represented by lines. G–U wobble base pairs are represented by dots.

This Article

  1. Published in Advance April 1, 2021, doi: 10.1261/rna.078694.121 RNA 27: 694-709

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