A noncanonical microRNA derived from the snaR-A noncoding RNA targets a metastasis inhibitor

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 1.
FIGURE 1.

Target-oriented microRNA discovery (TOMiD) workflow. Following Ago-qCLASH, reads with partial alignments are evaluated as hybrids based on counts and biochemical parameters. Enrichment/suppression of candidate miRNAs is then calculated by comparison of the normalized counts in Drosha/Dicer conditions to wild-type, and the combined ScoreDrosha/Dicer is calculated (see details in Supplemental Methods).

This Article

  1. Published in Advance April 1, 2021, doi: 10.1261/rna.078694.121 RNA 27: 694-709

Current Issue

  1. August 2026, 32 (8)
  1. Current Issue
  1. Alert me to new issues of RNA