Interaction interfaces of the Ebp1-ribosome complex. (A) Ebp1 (green)-ribosome (60S subunit [rRNA in light blue and ribosomal proteins in gray]) complex is represented as surface in two orientations. (B) Overview of Ebp1 binding site on human ribosome. Ebp1 (green), eL19 (yellow), uL23 (magenta), uL24 (orange), uL29 (wheat) proteins, fragment of 5.8S rRNA (purple), and different regions (H53, H59, and ES27L) of the 28S rRNA (light blue) are shown as cartoons. (C–E) Closer view of interaction interface of Ebp1 (green) with eL19 (yellow) and H59 (light blue), uL23 (magenta), and H53 (light blue), and uL29 (wheat) and 5.8S rRNA (purple). Interacting residues are shown as sticks, and polar interactions are marked by dotted lines.
